HUNTER R.SMITH, MD

Hunter Russell Smith

Personal History

Present Position
Partner, Boulder Valley Pulmonology
1000 Alpine, Suite 100
Boulder, CO 80304
(303) 442-2150

Research
Investigator
Alpine Clinical Research Center
1000 Alpine, Suite 200
Boulder, CO 80304
(303) 443-7229

Rank
Assistant Professor of Medicine
University of Colorado Health Sciences Center

Educational History
University of Colorado, Boulder, B.A. 1971

University of Colorado School of Medicine, Denver
M.D. 1980

Intern in Medicine, Yale-New Haven Hospital, New Haven 1980-81

Research Fellow in Clinical Oncology, UCHSC, Denver 1981-82

Resident in Medicine, Yale-New Haven Hospital, New Haven and University of Colorado Health Sciences Center (UCHSC), Denver 1981-84

Chief Medical Resident, UCHSC, Denver 1984-85

Clinical Fellow in Pulmonary and Critical Care Medicine, UCHSC, Denver 1985-86

Research Fellow in Pulmonary Medicine, UCHSC, Denver 1986-88

Licensure and Certification
1982 Colorado License Registration No. 24423
1985 American Board of Internal Medicine
1988 American Board of Internal Medicine, Pulmonary Disease Subspeciality
1990 American Board of Internal Medicine, Critical Care Certification

Professional Positions
1984-85
Chief Medical Resident, University of Colorado Health Sciences Center, Denver, Colorado

1987-88
Instructor, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado

1987-92
Staff Physician, Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado

1988-present
Assistant Professor of Medicine, University of Colorado Health Sciences Center, Denver, Colorado

1989-92
Director, Adult Special Care Unit, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado

1992-present
Staff Physician, Boulder Community Hospital, Boulder, Colorado and Avista Hospital, Louisville, Colorado

1992-93
President, Internal Medical Department, Avista Hospital, Louisville, Colorado

1993-present
Director, Intensive Care Unit, and Head, Critical Care Committee, Boulder Community Hospital, Boulder, Colorado

1994-present
Medical Executive Committee, Avista Hospital, Louisville, Colorado

Honors and Awards
Archibald Buchannan Award, University of Colorado Health Sciences Center 1977

Alton R. Christensen Scholarship, University of Colorado Health Sciences Center 1978

Alpha Omega Alpha, University of Colorado Health Sciences Center 1979

Gold Headed Cane Award, University of Colorado Health Sciences Center 1980

Professional Affiliations
Associate Member, American College of Physicians 1985-present

Associate Member, American Thoracic Society 1987-present

Council Member, American Lung Association of Colorado, Flatirons Division 1987-1988

Professional Service and Committees
Institutional and Departmental Committees
1985 Attending physician, Denver Veterans Administration Hospital, Denver, Colorado

1987-92 Attending Physician Department of Medicine and Adult Special Care Unit, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado

Review and Referee Activities
1987-90 Reviewer, American Review of Respiratory Disease

1991 Reviewer, Chest

Teaching Activities
Course Director
1988-90 Instructor, Pulmonary Pathophysiology, University of Colorado, Physician Therapy Program, Denver, Colorado

1987-88 Instructor, Introduction to Clinical Medicine, University of Colorado School of Medicine, Denver, Colorado

1985-90 Lab Instructor for Pulmonary Pathophysiology Course, University of Colorado School of Medicine, Denver, Colorado

1984-85 Instructor, Physical Diagnosis Course, University of Colorado School of Medicine, Denver, Colorado

1978 Assistant Instructor of Basic Anatomy, University of Colorado School of Medicine, Denver, Colorado

Teaching Activities
Graduate and Medical School Lectures
1990-91 Lecturer, University of Colorado School of Medicine, Family Practice Review Course, Denver, Colorado

1990 Lecturer, University of Colorado School of Medicine, Internal Medicine Course, Estes Park, Colorado. New concepts in the Treatment of Reversible Airway Obstruction

1991 Lecturer, American Association of Laboratory Animal Science, Winter Park, Colorado. Animal Models of Asthma

1991 Lecturer, Department of Medicine, Acute Care Lecture Series. Acute Asthma

Research Grants, Contracts and Special Grants
NIH# 36577 Inflammation, Airways Reactivity and Asthma
NIH Program Project Grant
Program Director: Gary Larsen, M.D.
Project #1, Immune and Inflammatory reactions in Human Allergic Asthma
P.I.: Lanny Rosenwasser, M.D.
Award Period: 7/1/91 – 6/30/95
Total Budget: $3,645,392

NIH# 36577 Inflammation, Airways Reactivity and Asthma
NIH Program Project Grant
Program Director: Gary Larsen, M.D.
Project #1, Pathogenesis of the Late Asthmatic Response
P.I.: Gary Larsen, M.D.
Award Period: 7/1/86 – 6/30/91
Total Budget: $4,002,105

Edward Livingston Trudeau Scholar, American Lung Assoc.
P.I.: Hunter R. Smith, M.D.
Award Period: 1988 – 1991
Total Award Budget: $75,000

Bibliography
Papers Published in Referred Journals

Peterson J. Hansbrough, J, Buerk W, Rundus C, Walner S, Smith H, and Robinson W. Regulation of granulopoiesis following severe thermal injury. J. Trauma 23:19, 1983

Geier JM, Smith H, Braun T, Gross C, Kindt GW, and Glode LM. Extracerebral toxicity of continuous intracarotid FUDR via implanted Infusaid pump in brain tumor patients. Surg Forum 34: 530-532, 1983

Smith HR, Geier JM, Stears J, Kindt GW, and Glode LM. Intracarotic BCNU in the treatment of malignant brain tumors. Clin Res 31:1-3, 1983

Mughal TI, Glode LM, Smith H, Geier JM, Braunt T, Klingensmith W, and Kindt GW. Phase I clinical trial of intracarotid bis-chloroethylnitrosourea (BCNU) and 2’deoxy-5-fluorouridine (FUDR) in malignant astrocytomas. J. Neuro-Oncology 3:291-296, 1986

Wenzel SE, Westcott JY, Smith HR, and Larsen GL. Spectrum of prostanoid release after bronchoaveolar allergen challenge in atopic asthmatics and in control groups. AM Rev Respir Dis 139: 450-457, 1989

Welsh CH, Watters LC, Harbeck RJ, Smith HR. Indolent staphylococus aureus pneumonia. Western J Med 153:316-319, 1990

Martin RJ, Cicutto LC, Smith HR, Ballard RD, Ballard RD, Szefler SJ. Airways inflammation in nocturnal asthma. Am Rev Respir Dis,
143:351-357, 1991

Westcott JY, Smith HR, Martin RJ, Wenzel SE, Larsen GL, Batt RA, Voelkel NK. Urine LTE₄ levels in asthmatics. Am Rev Respir Dis, 1991

Books and Reviews
Smith HR, and Henson PM. Mediators of asthma. Sem Respirt Med 8:287-301, 1987

Larsen GL, Uchida DA, and Smith HR. Late Phase Reactions: Mechanisms. In: New Developments in Mechanisms and Treatment of Bronchial Obstruction, Dijkman JH and Kerribijn KF, eds., Astra Respiratory, Rijswijk, The Netherlands, pp 19-30, 1988

Smith HR. Sudden Onset of Wheezing and Dyspnea. In: Pulmonary Grand Rounds, Schwarz MI, ed, B.C. Decker, Inc. Ontario, pp 263-268, 1989
Smith.6

Smith HR. Intermittent Wheezing. In: Pulmonary Grand Rounds, Schwarz, MI, ed., B.C. Decker, Inc., Ontario, pp 269-275, 1989

Smith HR. Respiratory Failure in a Hospitalized Patient with Known Asthma. In: Pulmonary Grand Rounds, Schwarz MI, ed, B.C. Decker, Inc., Ontario, pp 276-282, 1989

Clinical Research Experience

Sponsor          Indication                 Year
Glaxo 5018    Adult Asthma                        1995-96
Glaxo 3011    Adolescent & Adult Asthma  1995-96
Glaxo 2016    Pediatric Asthma                1996
Glaxo 3014    Pediatric Asthma                1996
SmithKline Beecham Adolescent & Adult Asthma 1996
SmithKline Beecham COPD                        1997
Novartis            COPD                                        1997
Rhone-Poulenc Rorer Asthma                        1998
Novartis            COPD                                        1998